The first lady will speak at Hampton University in Holland Hall located at 160 Marshall Ave.
Doors for the event open at 12:30 P.M. The event is free and open to the public, but tickets are required.
Tickets are available at the Obama campaign office in Hampton, 1026 Settlers Landing Road; the Newport News campaign offices located at 11717 Jefferson Avenue and 2712 Chestnut Avenue; and at the Hampton University Convocation Center Box Office, 700 Emancipation Drive, Hampton.
Tickets are available on Wednesday from 5 p.m. to 9 p.m.; and if still available Thursday from 8 a.m. to 9 p.m.
This will mark Michelle Obama's first campaign stop on the Peninsula this election cycle. She held an event with the president in October 2011 in Hampton where she discussed a veterans' jobs program and the president pushed Congress to pass his American Jobs Act.
The first lady will also hold an event at Virginia State University in Petersburg on Friday afternoon.
As Election Day approaches, the spouses of the presidential candidates have been frequent visitors to Virginia.
Obama and Romney are in a virtual dead-heat in the Old Dominion. As a key battleground state, the commonwealth is seen as a must win for either candidate's path to the White House.